Antimicrobial Activity and Chemical Composition of Albanian Oregano

Antimicrobial activity of methanolic and aqueous methanolic extracts of oregano was tested against: Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 6538, Pseudomonas spp, Candida albicans ATCC 10231, Listeria monocytogenes ATCC 19111 and Salmonella typhimurium ATCC 14028. Antimicrobial activity of oregano essential oil was also tested against: E.coli, P.aeruginosa, S.aureus and C. albicans. Only oregano essential oil was active against microorganisms selected. Essential oil of oregano was analysed by GC-MS. Eighteen components were identified representing 99.48% of the oil. Monoterpenes phenols and derivatives (borneol, 4-terpineol, carvacrol methyl ether, thymoquinone, thymol, carvacrol) represented 74.66 % of essential oil. Carvacrol, p-cymene, thymol and γ-terpinene were the main components. Sesquiterpenes such as trans-caryophyllene, α-humulene, β-bisabolene, δ-Cadinene, caryophyllene oxide were also found

Microbiologically Contaminated and Over-Preserved Cosmetic Products According Rapex 2008-2014

We investigated the Rapid Alert System (RAPEX) database from January 2008 until week 26 of 2014 to give information to consumers about microbiologically contaminated cosmetics and over-preserved cosmetic products. Chemical risk was the leading cause of the recalls (87.47%). Sixty-two cosmetic products (11.76%) were recalled because they were contaminated with pathogenic or potentially pathogenic microorganisms. Pseudomonas aeruginosa was the most frequently found microorganism. Other microorganisms found were: Mesophilic aerobic microorganisms, Staphylococcus aureus, Candida albicans, Enterococcus spp., Enterobacter cloacae, Enterococcus faecium, Enterobacter gergoviae, Rhizobium radiobacter, Burkholderia cepacia, Serratia marcescens, Achromabacter xylosoxidans, Klebsiella oxytoca, Bacillus firmus, Pantoea agglomerans, Pseudomonas putida, Klebsiella pneumoniae and Citrobacter freundii. Nine cosmetic products were recalled because they contained methylisothiazolinone (0.025%–0.36%), benzalkonium chloride (1%), triclosan (0.4%) in concentrations higher than the limits allowed by European Regulation 1223/2009. Fifteen products were recalled for the presence of methyldibromo glutaronitrile, a preservative banned for use in cosmetics. Thirty-two hair treatment products were recalled because they contained high concentrations of formaldehyde (0.3%–25%)

Quantitative determination of phenolics compounds in Origanum vulgare extract by high-performance liquid chromatography coupled with tandem mass spectrometric detection

Phenolic compounds in 80% MeOH extract of oregano (Origanum vulgare L.) were analysed by reversed phase HPLC, follewed by tandem mass spectrometric detection. For the first time thirty nine phenolics, corresponding to flavonoids, flavonoid glycosides, benzoic acids, cinnamic acids, coumarins and lignans were quantified in oregano extract. Quinic acid, naringenin, luteoline-7-O-glucoside, caffeic acid, apigenin and luteolin were the most abundant phenols detected in oregano extract

Effects of different essential oils on HaCat keratinocytes against hydrogen peroxide induced oxidative stress

The effect of different concentrations of common juniper, oregano, laurel, lavander, sage and myrtie essential oils on human skin cell HaCat in vitro was explored. This study has demonstrated that all essential oils were cytotoxic to human keratinocytes in vitro at a concentration of 1% (v/v). At a concentration of 0.1%, all essential oils, with the exception of Laurus nobilis L., were still irritating. At lower concentrations all essential oils showed no toxicity and no protective effect on HaCat human keratinocytes from oxidative stress induced by exposure to hydrogen peroxide

New Technologies in Rice Derivatives

In this research the incapsulation of ferulic acid (FA) in advanced systems of protection with the aim of improving its stability and photostability was studied. Lipoparticles and polymeric microparticles as incapsulation systems were prepared and characterized. Lipoparticles were completely of natural origin, while microparticles were obtained using chitosan as natural polymer. In both systems FA stability was greatly increased and its organoleptic properties in the emulsions did not change.

Green Cosmetic Surfactant from Rice: Characterization and Application

During recent years, microwave irradiation has been extensively used for performing green organic synthesis. The aim of this study was to synthesize, through a microwave-assisted irradiation process, a natural surfactant with O/W emulsifying properties. Our attention was focused on polyglycerol esters of fatty acids that are biocompatible and biodegradable non-ionic surfactants widely used in food and cosmetic products. The emulsifier was obtained using vegetable raw material from renewable sources: polyglycerol derived from vegetable glycerol and rice bran oil fatty acids. The natural emulsifier obtained was then characterized and evaluated for its emulsifying properties using different doses, oil phases, rheological additives, waxes, etc. The potential application in solar products, in comparison with other natural emulsifiers, was also evaluated

Synthesis, Crystal Structure and properties of N,N-Dimethyl-N-(6-(benzoyl-4-phenoxy)hexamethylen)-N-n-dodecyl-ammonium bromide: a new substantive UV filter.

Inprevious paper we have described the synthesis, the substantivity and the antibacterial activity of 4-hydroxy and 2,4-dihydroxy benzophenone derivatives. These properties were affected by the lenght of the n-alkyl chain bonded to the quaternary nitrogen. It would have been of interest to take into consideration also the effect on these properties of the lenght to the methylene chain connecting the oxygen and quaternary nitrogen atoms. In this view we have synthesized N,N-dimethyl-N-(6-(benzoyl-4-phenoxy)hexamethylen)-N-n-dodecil ammonium bromide. Substantivity and antimicrobial properties of this compound have been evaluated and the conformation in the solid state has been determined by single crystal X-ray diffraction. The conformation of the molecule which has been shown to play a fondamental role for the antibacterial activity of these compounds presents an extensive folding of the n-dodecyl chain back towards and along the aromatic moiety. Coiled conformations that have been associated with antibacterial properties and skin irritation phenomena are absent